Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.61 |
| ▸ | HTR1D | P28221 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6597392 | 0.99 | HTR1A (0.60) | HTR1AHTR1DKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6599492 | 0.89 | HTR1A (0.66) | HTR1AHTR1DKMT2AALDH1A1MAPT | |
| SCHEMBL7970947 | 0.89 | HTR1A (0.50) | HTR1AHTR1DKMT2AALDH1A1MAPT | |
| SCHEMBL7970944 | 0.89 | HTR1A (0.50) | HTR1AHTR1DKMT2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL6598470 | 0.82 | HTR1A (0.79) | HTR1AHTR1DKMT2AALDH1A1MAPT | |
| SCHEMBL7984579 | 0.80 | ACHE (0.52) | HTR1AKMT2AALDH1A1MEN1 | |
| SCHEMBL6598221 | 0.80 | HTR1A (0.62) | HTR1AHTR1DKMT2ADRD2MEN1 | |
| Hydrochloric Acid SCHEMBL5364551 | 0.79 | ACHE (0.51) | HTR1AKMT2AALDH1A1MEN1 | |
| SCHEMBL6600129 | 0.79 | HTR1A (0.55) | HTR1AHTR1DKMT2AALDH1A1MAPT | |
| SCHEMBL6600132 | 0.79 | HTR1A (0.55) | HTR1AHTR1DKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | claimed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | claimed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | claimed |
| EP-1008594-B1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA LAB (ES) | 2004-03-17 | — | — | EP | disclosed |
| US-6262056-B1 | TREATING ANXIETY OR DEPRESSION | VITA-INVEST, SA (ES) | 2001-07-17 | — | — | US | disclosed |
| EP-1008594-A1 | COMPOUNDS DERIVED FROM THOPHENE AND BENZOTHIOPHENE, AND RELATED UTILISATION AND COMPOSITION | VITA-INVEST, S.A. (ES) | 2000-06-14 | — | — | EP | disclosed |