Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 10/20 | 0.56 |
| ▸ | FEN1 | P39748 | 10/20 | 0.56 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | F2 | P00734 | 3/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6237306 | 0.82 | ALOX5AP (0.77) | ALOX5APFEN1F10 | |
| SCHEMBL8350056 | 0.78 | CA1 (0.54) | ALOX5APFEN1 | |
| SCHEMBL6237302 | 0.78 | ALOX5AP (0.53) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL6548544 | 0.74 | F10 (0.52) | ALOX5APFEN1F10 | |
| SCHEMBL5488230 | 0.73 | CA2 (0.56) | ALOX5APFEN1 | |
| SCHEMBL16177854 | 0.73 | ALOX5AP (0.48) | ALOX5APFEN1 | |
| SCHEMBL3398528 | 0.73 | ALOX5AP (0.56) | ALOX5APFEN1F10F2PRSS1 | |
| SCHEMBL48885 | 0.73 | CA2 (0.52) | ALOX5APFEN1F10 | |
| SCHEMBL13733557 | 0.73 | ALOX5AP (0.51) | ALOX5APFEN1 | |
| SCHEMBL1080972 | 0.72 | CA2 (0.61) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207697-B1 | AMIDINYL-SUBSTITUTED RINGS; ANTICOAGULANTS; THROMBOEMBOLIC DISORDERS; ANTIISCHEMIC AND ANTIINFLAMMATORY AGENTS; STROKES; SERINE PROTEASE INHIBITORS | DUPONT PHARMACEUTICALS COMPANY | 2001-03-27 | — | — | US | disclosed |