Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 12/20 | 0.56 |
| ▸ | FEN1 | P39748 | 12/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2567683 | 0.76 | KIF11 (0.56) | ALOX5APFEN1TRPV1F10 | |
| SCHEMBL13733557 | 0.75 | ALOX5AP (0.51) | ALOX5APFEN1CA1CA2CA4 | |
| SCHEMBL29718617 | 0.75 | CYP3A4 (0.47) | ALOX5APFEN1TRPV1F10 | |
| SCHEMBL6237306 | 0.74 | ALOX5AP (0.77) | ALOX5APFEN1F10 | |
| SCHEMBL29718800 | 0.74 | ALOX5AP (0.45) | ALOX5APFEN1F2PRSS1PRSS2 | |
| SCHEMBL8350056 | 0.73 | CA1 (0.54) | ALOX5APFEN1CA1CA2CA4 | |
| SCHEMBL7970970 | 0.73 | ALOX5AP (0.56) | ALOX5APFEN1F2PRSS1F10 | |
| SCHEMBL6883474 | 0.73 | KIF11 (0.50) | ALOX5APFEN1TRPV1 | |
| SCHEMBL30810325 | 0.72 | BCAT2 (0.54) | ALOX5APFEN1 | |
| SCHEMBL15932372 | 0.72 | ALOX5AP (1.00) | ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2245017-A2 | NOVEL HETEROCYCLES | Orchid Research Laboratories Limited (IN) | 2010-11-03 | — | — | EP | claimed |
| WO-2009095773-A2 | NOVEL HETEROCYCLES | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2009-08-06 | — | — | WO | claimed |