Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 1/20 | 0.69 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.67 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.67 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | NAMPT | P43490 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973291 | 0.90 | OPRK1 (0.65) | CXCR4GRIN1GRIN2AGRIN2BMAPT | |
| SCHEMBL19358860 | 0.88 | CXCR4 (0.82) | CXCR4KEAP1MAPTNAMPTHTT | |
| SCHEMBL996398 | 0.86 | KEAP1 (0.71) | CXCR4KEAP1MAPTNAMPTHTT | |
| SCHEMBL19358847 | 0.82 | CXCR4 (0.77) | CXCR4GRIN1GRIN2AGRIN2BKEAP1 | |
| SCHEMBL19358887 | 0.82 | MAPT (0.82) | CXCR4MAPTHTTCA12CA9 | |
| SCHEMBL19358855 | 0.82 | CXCR4 (1.00) | CXCR4KEAP1MAPTNAMPTHTT | |
| SCHEMBL30254760 | 0.82 | CXCR4 (0.78) | CXCR4KEAP1MAPTHTTHDAC8 | |
| SCHEMBL15348918 | 0.81 | GRIN1 (1.00) | CXCR4GRIN1GRIN2AGRIN2BMAPT | |
| SCHEMBL29557264 | 0.81 | GRIN1 (1.00) | CXCR4GRIN1GRIN2AGRIN2BMAPT | |
| SCHEMBL1079531 | 0.81 | NAMPT (0.67) | CXCR4KEAP1MAPTNAMPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |