Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.65 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.64 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.64 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.61 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7970997 | 0.90 | CXCR4 (0.69) | OPRK1GRIN1GRIN2AGRIN2BMAPT | |
| SCHEMBL1049418 | 0.85 | TSHR (0.68) | OPRK1MAPTALDH1A1KMT2AOPRM1 | |
| SCHEMBL2831966 | 0.83 | CYP19A1 (0.78) | OPRK1ALDH1A1CYP19A1CA12CA9 | |
| SCHEMBL5960098 | 0.83 | KEAP1 (0.76) | OPRK1MAPTALDH1A1CXCR4CYP19A1 | |
| SCHEMBL4927135 | 0.80 | HDAC6 (0.68) | OPRK1MAPTCXCR4HDAC8HDAC6 | |
| SCHEMBL19358860 | 0.79 | CXCR4 (0.82) | OPRK1MAPTALDH1A1OPRM1CXCR4 | |
| SCHEMBL30254760 | 0.79 | CXCR4 (0.78) | OPRK1MAPTALDH1A1CXCR4HDAC8 | |
| SCHEMBL6352806 | 0.79 | MEN1 (0.61) | OPRK1MAPTALDH1A1KMT2AOPRM1 | |
| SCHEMBL15348918 | 0.78 | GRIN1 (1.00) | GRIN1GRIN2AGRIN2BMAPTKMT2A | |
| SCHEMBL29557264 | 0.78 | GRIN1 (1.00) | GRIN1GRIN2AGRIN2BMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |