Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587430 | 0.79 | ALDH1A1 (0.50) | ALDH1A1KDM4EUSP2TSHRHCAR2 | |
| SCHEMBL7988667 | 0.79 | KDM4E (0.31) | ALDH1A1KDM4EUSP2TSHR | |
| SCHEMBL7988196 | 0.74 | KDM4E (0.50) | ALDH1A1KDM4EUSP2TSHRHCAR2 | |
| SCHEMBL8135897 | 0.72 | ALDH1A1 (0.48) | ALDH1A1KDM4EUSP2TSHRHCAR2 | |
| SCHEMBL6587396 | 0.70 | KDM4E (0.40) | ALDH1A1KDM4EUSP2TSHRLMNA | |
| SCHEMBL6585945 | 0.68 | KMT2A (0.43) | ALDH1A1KDM4EUSP2TSHRLMNA | |
| SCHEMBL5704533 | 0.67 | LMNA (0.48) | ALDH1A1KDM4EUSP2TSHRLMNA | |
| SCHEMBL7980960 | 0.67 | KDM4E (0.39) | ALDH1A1KDM4EUSP2TSHRHCAR2 | |
| SCHEMBL8517597 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNAMAPK1KMT2A | |
| SCHEMBL8687749 | 0.66 | LMNA (0.34) | ALDH1A1LMNAMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245716-B1 | LOW DOSAGE; NONPHYTOTOXIC | NIPPON SODA CO., LTD. (JP) | 2001-06-12 | — | — | US | disclosed |