Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325316 | 0.88 | SMN1; SMN2 (0.43) | ALDH1A1MEN1KMT2ARAB9AKDM4E | |
| SCHEMBL5319750 | 0.85 | MEN1 (0.41) | ALDH1A1MEN1KMT2ASMN1; SMN2BLM | |
| SCHEMBL5328017 | 0.85 | KMT2A (0.40) | MEN1KMT2AEGFRSRCLMNA | |
| SCHEMBL5320461 | 0.83 | BLM (0.38) | ALDH1A1MEN1KMT2ARAB9AHSP90AA1 | |
| SCHEMBL1528022 | 0.78 | KMT2A (0.44) | MEN1KMT2ARAB9ATSHRCYP11B1 | |
| SCHEMBL8806580 | 0.78 | KMT2A (0.44) | ALDH1A1MEN1KMT2ACYP11B1CYP11B2 | |
| SCHEMBL8170659 | 0.77 | TBXAS1 (0.41) | ALDH1A1MEN1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL584666 | 0.76 | KMT2A (0.43) | MEN1KMT2ARAB9ATSHRCYP11B1 | |
| SCHEMBL6446028 | 0.76 | KMT2A (0.43) | MEN1KMT2ACYP11B1CYP11B2KDM4E | |
| SCHEMBL8806973 | 0.75 | KMT2A (0.42) | ALDH1A1MEN1KMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316436-B1 | ANTICANCER AGENTS | MERCK & CO., INC. | 2001-11-13 | — | — | US | disclosed |