Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 5/20 | 0.44 |
| ▸ | NQO2 | P16083 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20595409 | 0.82 | KDM4E (0.53) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7982444 | 0.77 | KDM4E (0.53) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7981239 | 0.76 | MAPT (0.53) | EGFRALDH1A1MAPTHTTSRC | |
| SCHEMBL14313953 | 0.75 | GPR3 (0.71) | KDM4EALDH1A1HPGDHSD17B10GPR3 | |
| SCHEMBL31670425 | 0.74 | KDM4E (0.66) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| Bicarbonate SCHEMBL9678990 | 0.73 | GPR3 (0.76) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL9623265 | 0.73 | POLB (0.53) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL19177352 | 0.72 | WDR5 (0.47) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11250963 | 0.72 | EGFR (0.56) | EGFRKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL14124824 | 0.72 | KDM4E (0.73) | EGFRKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5854273-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 1998-12-29 | — | — | US | disclosed |