Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | EGFR | P00533 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 4/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.39 |
| ▸ | FABP4 | P15090 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31670425 | 0.81 | KDM4E (0.66) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL7971245 | 0.77 | EGFR (0.53) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL21043614 | 0.74 | EGFR (0.57) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL5337894 | 0.72 | ALDH1A1 (0.50) | KDM4EALDH1A1HPGDHSD17B10GLA | |
| SCHEMBL20595409 | 0.71 | KDM4E (0.53) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL24010348 | 0.71 | ALKBH5 (0.56) | KDM4EEGFRALDH1A1HPGDHSD17B10 | |
| SCHEMBL26214696 | 0.71 | KDM4E (0.64) | KDM4EMAPTALDH1A1HPGDHSD17B10 | |
| SCHEMBL11250963 | 0.71 | EGFR (0.56) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL984736 | 0.71 | EGFR (0.65) | KDM4EMAPTEGFRALDH1A1HPGD | |
| SCHEMBL30443220 | 0.71 | EGFR (0.65) | KDM4EMAPTEGFRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300340-B1 | USEFUL FOR THERAPY OF CANCER AND SOLID TUMORS | ADIR ET COMPAGNIE (FR) | 2001-10-09 | — | — | US | disclosed |
| US-6162822-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 2000-12-19 | — | — | US | disclosed |
| US-5854273-A | Bisimide compounds | ADIR ET COMPAGNIE (FR) | 1998-12-29 | — | — | US | disclosed |