Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 16/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 16/20 | 0.36 |
| ▸ | ADRA1B | P35368 | 16/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7971010 | 0.83 | ADRA1A (0.53) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7707903 | 0.77 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL7707906 | 0.77 | ADRA1D (0.47) | ADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL7707365 | 0.76 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL7707363 | 0.76 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BKCNH2 | |
| SCHEMBL7971286 | 0.74 | ADRA1A (0.37) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7166525 | 0.74 | ADRA1A (0.37) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7964947 | 0.73 | ADRA1A (0.55) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7966089 | 0.73 | ADRA1A (0.53) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7082192 | 0.69 | ADRA1D (0.68) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6255315-B1 | BENIGN PROSTATIC HYPERPLASIA | MERCK & CO., INC. | 2001-07-03 | — | — | US | disclosed |
| US-6037354-A | ADMINISTERING PHENYL-SUBSTITUTED THIAZOLIDIN-4-ONE OR OXAZOLIDIN-2-ONE DERIVATIVE TO TREAT BENIGN PROSTATE HYPERPLASIA; SIDE EFFECT REDUCTION | MERCK & CO., INC. (US) | 2000-03-14 | — | — | US | disclosed |