Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819685 | 0.85 | KMT2A (0.57) | MAPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6819680 | 0.79 | ALDH1A1 (0.57) | MAPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6814823 | 0.75 | MAPK1 (0.51) | MAPK1ALDH1A1LMNAMAPTNPC1 | |
| SCHEMBL2961232 | 0.75 | ALDH1A1 (0.45) | MAPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6815404 | 0.73 | ALDH1A1 (0.63) | MAPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6819658 | 0.72 | MAPK1 (0.71) | MAPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL4050842 | 0.71 | ALDH1A1 (0.74) | ALDH1A1LMNAKDM4EMAPTNPC1 | |
| SCHEMBL2959759 | 0.71 | LMNA (0.48) | ALDH1A1LMNAKDM4EMAPTPOLB | |
| SCHEMBL5446693 | 0.71 | MAPK1 (0.75) | MAPK1ALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL17956801 | 0.70 | ALDH1A1 (0.68) | MAPK1ALDH1A1LMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |