Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974714 | 0.83 | MAPT (0.35) | ALDH1A1TDP1ALOX15CYP1A2CYP3A4 | |
| SCHEMBL7961496 | 0.81 | ALDH1A1 (0.46) | ALDH1A1TDP1ALOX15USP2PDE4A | |
| SCHEMBL16670930 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TDP1ALOX15USP2PDE4D | |
| SCHEMBL11850612 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TDP1ALOX15USP2PDE4D | |
| SCHEMBL11848082 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TDP1ALOX15USP2PDE4D | |
| SCHEMBL4449957 | 0.75 | ALDH1A1 (0.60) | ALDH1A1TDP1ALOX15USP2PDE4D | |
| SCHEMBL7977541 | 0.73 | CYP4F2 (0.35) | ALDH1A1TDP1ALOX15USP2CYP4F2 | |
| SCHEMBL11004376 | 0.73 | ALDH1A1 (0.52) | ALDH1A1TDP1ALOX15USP2CYP4F2 | |
| SCHEMBL7424483 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TDP1ALOX15USP2CYP1A2 | |
| SCHEMBL7293121 | 0.72 | ALDH1A1 (0.54) | ALDH1A1TDP1ALOX15USP2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |