Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 3/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TNF | P01375 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7961051 | 0.90 | ALDH1A1 (0.37) | APEX1ALDH1A1KMT2AMEN1 | |
| SCHEMBL7974447 | 0.88 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1TDP1CYP3A4 | |
| SCHEMBL7977575 | 0.82 | RAB9A (0.46) | ALDH1A1CYP1A2TSHRCYP3A4KMT2A | |
| SCHEMBL7971427 | 0.80 | CYP1A2 (0.36) | CYP4F2CYP4A11NAMPTALDH1A1CYP1A2 | |
| SCHEMBL7971395 | 0.73 | ALDH1A1 (0.44) | CYP4F2CYP4A11APEX1NAMPTALDH1A1 | |
| SCHEMBL7974479 | 0.70 | IMPDH1 (0.37) | ALDH1A1TDP1TSHRALOX15HSD17B10 | |
| SCHEMBL7329653 | 0.69 | TDP1 (0.66) | CYP4F2CYP4A11APEX1ALDH1A1CYP1A2 | |
| SCHEMBL7974475 | 0.68 | CYP4F2 (0.43) | CYP4F2CYP4A11APEX1TDP1CYP3A4 | |
| SCHEMBL798044 | 0.67 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1KMT2AMEN1 | |
| SCHEMBL7974599 | 0.67 | CYP4F2 (0.44) | CYP4F2CYP4A11ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10273469-A | — | — | None | — | — | JP | disclosed |
| US-6326369-B1 | ALZHEIMER'S DISEASE | TAKEDA CHEMICALS INDUSTRIES, LTD. (JP) | 2001-12-04 | — | — | US | disclosed |
| JP-H10273469-A | BICYCLIC QUINONE DERIVATIVE, PRODUCTION AND AGENT | TAKEDA CHEM IND LTD | 1998-10-13 | — | — | JP | disclosed |