Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 10/20 | 0.59 |
| ▸ | MMP9 | P14780 | 8/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | MMP1 | P03956 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | BMP1 | P13497 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 4/20 | 0.48 |
| ▸ | MMP13 | P45452 | 3/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516345 | 0.93 | MMP2 (0.57) | MMP2MMP9EGFRERBB2MMP1 | |
| SCHEMBL7971077 | 0.90 | MMP9 (0.53) | MMP2MMP9MMP1TP53MAPT | |
| SCHEMBL7970164 | 0.88 | MMP2 (0.62) | MMP2MMP9MMP1MAPTPOLB | |
| SCHEMBL7976158 | 0.86 | MMP9 (0.58) | MMP2MMP9EGFRERBB2BMP1 | |
| SCHEMBL8119279 | 0.82 | HDAC8 (0.58) | MMP2MMP9MMP1MMP3HDAC3 | |
| SCHEMBL7381656 | 0.81 | MMP2 (0.75) | MMP2MMP9MMP1MAPTBMP1 | |
| SCHEMBL7381660 | 0.81 | MMP2 (0.75) | MMP2MMP9MMP1MAPTBMP1 | |
| SCHEMBL28745570 | 0.81 | MMP2 (0.67) | MMP2MMP9MMP1MAPTPOLB | |
| SCHEMBL6081543 | 0.80 | MMP2 (0.86) | MMP2MMP9MMP1MAPTPOLB | |
| SCHEMBL22234044 | 0.80 | MMP2 (0.86) | MMP2MMP9MMP1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |