Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 6/20 | 0.52 |
| ▸ | MMP1 | P03956 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.46 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.46 |
| ▸ | BMP1 | P13497 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7959981 | 0.91 | NPY5R (0.55) | MMP9MMP2F2POLBNPY5R | |
| SCHEMBL7971489 | 0.90 | MMP2 (0.59) | MMP9MMP2MMP1MMP13POLB | |
| SCHEMBL7971563 | 0.87 | KAT6A (0.53) | MMP9MMP2F2MMP1MMP13 | |
| SCHEMBL27516345 | 0.87 | MMP2 (0.57) | MMP9MMP2MMP1MMP13POLB | |
| SCHEMBL8647491 | 0.87 | MMP2 (0.69) | MMP9MMP2F2MMP1MMP13 | |
| SCHEMBL8389137 | 0.87 | MMP2 (0.69) | MMP9MMP2F2MMP1MMP13 | |
| SCHEMBL7970018 | 0.80 | CTSL (0.56) | F2KDM4EALDH1A1 | |
| SCHEMBL6021666 | 0.78 | CTSS (0.58) | MMP9MMP2MMP1MMP13ADAM17 | |
| SCHEMBL7970164 | 0.78 | MMP2 (0.62) | MMP9MMP2MMP1MMP13POLB | |
| SCHEMBL3088714 | 0.78 | KDM4E (0.58) | MMP9MMP2F2MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271247-B1 | BINDING TO NEUROPEPTIDE RECEPTORS | ADIR ET COMPAGNIE (FR) | 2001-08-07 | — | — | US | disclosed |
| US-6172108-B1 | NEUROPEPTIDE Y RECEPTOR LIGANDS; TREATING PSYCHOLOGICAL, EATING, SLEEP, AND SEXUAL DISORDERS; HYPOTENSIVE, ANXIOLYTIC, ANTIDEPRESSANT, AND ANTIDIABETIC AGENTS | ADIR ET COMPAGNIE (FR) | 2001-01-09 | — | — | US | disclosed |
| EP-1010691-A2 | Hydrazide derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2000-06-21 | — | — | EP | disclosed |