Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 9/20 | 0.44 |
| ▸ | DRD2 | P14416 | 5/20 | 0.40 |
| ▸ | KDM1A | O60341 | 4/20 | 0.39 |
| ▸ | GSK3B | P49841 | 2/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | GRK2 | P25098 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7986100 | 0.99 | HTR7 (0.44) | HTR7DRD2KDM1AGSK3BLYN | |
| SCHEMBL7986166 | 0.96 | HTR4 (0.42) | HTR7GSK3BLYNGRK2CLK1 | |
| Hydrochloric Acid SCHEMBL7971705 | 0.95 | HTR4 (0.41) | HTR7GSK3BLYNGRK2CLK1 | |
| SCHEMBL7983159 | 0.90 | HTR7 (0.43) | HTR7DRD2KDM1AHDAC6HTR1A | |
| SCHEMBL7986376 | 0.89 | HTR7 (0.43) | HTR7KDM1AGSK3BKCNH2 | |
| Hydrochloric Acid SCHEMBL7986997 | 0.89 | HTR7 (0.42) | HTR7DRD2KDM1AHDAC6HTR1A | |
| Hydrochloric Acid SCHEMBL7982153 | 0.89 | HTR7 (0.43) | HTR7KDM1AGSK3BKCNH2 | |
| SCHEMBL7989146 | 0.89 | HTR7 (0.49) | HTR7DRD2KDM1AHDAC6 | |
| Hydrochloric Acid SCHEMBL7983742 | 0.88 | HTR7 (0.49) | HTR7DRD2KDM1AHDAC6 | |
| SCHEMBL7971613 | 0.87 | KMT2A (0.41) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |