Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797737 | 0.77 | — | — | |
| SCHEMBL14481622 | 0.76 | — | — | |
| SCHEMBL8565629 | 0.72 | ALDH1A1 (0.31) | ALDH1A1TP53CYP3A4TSHRACHE | |
| SCHEMBL797774 | 0.72 | — | — | |
| SCHEMBL797777 | 0.71 | CYP3A4 (0.36) | CYP3A4TSHR | |
| SCHEMBL796937 | 0.71 | NOS3 (0.34) | — | |
| SCHEMBL7955998 | 0.71 | — | — | |
| SCHEMBL52748 | 0.70 | — | — | |
| SCHEMBL796864 | 0.70 | — | — | |
| SCHEMBL797336 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9062044-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2015-06-23 | — | — | US | claimed |
| EP-2491031-B1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-08-07 | — | — | EP | claimed |
| US-20130137672-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2013-05-30 | — | — | US | claimed |
| EP-2491031-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2012-08-29 | — | — | EP | claimed |
| WO-2011050202-A1 | FUSED HETEROCYCLIC COMPOUNDS AS OREXIN RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2011-04-28 | — | — | WO | claimed |
| EP-0102542-B1 | 1,2,4,6-THIATRIAZIN-1,1-DIOXIDE ETHERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES | BASF Aktiengesellschaft (DE) | 1990-07-04 | — | — | EP | claimed |
| EP-0207412-B1 | PROCESS FOR PREPARING ESTERS OF (THIONO)PHOSPHORIC ACID | BAYER AG (DE) | 1990-04-04 | — | — | EP | claimed |
| US-4772702-A | Preparation of (thiono)phosphoric esters | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-20 | — | — | US | claimed |
| EP-0022141-B2 | COMPOSITIONS AND METHODS FOR REDUCING HERBICIDAL INJURY | MONSANTO COMPANY (US) | 1987-12-02 | — | — | EP | claimed |
| EP-0207412-A2 | Process for preparing esters of (thiono)phosphoric acid | BAYER AG (DE) | 1987-01-07 | — | — | EP | claimed |
| US-4585472-A | PRE- AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | claimed |
| EP-0102542-A2 | 1,2,4,6-Thiatriazin-1,1-dioxide ethers, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1984-03-14 | — | — | EP | claimed |
| EP-0022141-B1 | COMPOSITIONS AND METHODS FOR REDUCING HERBICIDAL INJURY | MONSANTO COMPANY (US) | 1983-06-08 | — | — | EP | claimed |
| EP-2550264-B1 | PYRIDAZINE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS | BASF SE (DE) | 2016-06-08 | — | — | EP | disclosed |
| US-9062044-B2 | Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators | JANSSEN PHARMACEUTICA NV (BE) | 2015-06-23 | — | — | US | disclosed |
| US-9040537-B2 | Pyridazine compounds for controlling invertebrate pests | BASF SE (DE) | 2015-05-26 | — | — | US | disclosed |
| EP-0207412-A2 | Process for preparing esters of (thiono)phosphoric acid | BAYER AG (DE) | 1987-01-07 | — | — | EP | disclosed |
| US-4585472-A | PRE- AND POSTEMERGENCE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1986-04-29 | — | — | US | disclosed |
| EP-0102542-A2 | 1,2,4,6-Thiatriazin-1,1-dioxide ethers, process for their preparation and their use as herbicides | BASF Aktiengesellschaft (DE) | 1984-03-14 | — | — | EP | disclosed |
| EP-0022141-B1 | COMPOSITIONS AND METHODS FOR REDUCING HERBICIDAL INJURY | MONSANTO COMPANY (US) | 1983-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137672-A1 | DISUBSTITUTED OCTAHYDROPYRROLO[3,4-c]PYRROLES AS OREXIN RECEPTOR MODULATORS | HCRTR2, HCRTR1, OXTR | ALDH1A1 2359/4885TP53 4884/4885CYP3A4 2197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.