Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 6/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7969202 | 0.83 | NFE2L2 (0.38) | NFE2L2LMNAKMT2ACYP3A4TSHR | |
| SCHEMBL7969643 | 0.79 | NFE2L2 (0.38) | NFE2L2CYP3A4TSHRALDH1A1 | |
| SCHEMBL7958651 | 0.73 | NFE2L2 (0.56) | AHRNFE2L2LMNACYP3A4TSHR | |
| SCHEMBL7971487 | 0.73 | MAOB (0.35) | NFE2L2LMNAMEN1KMT2ATSHR | |
| SCHEMBL7971462 | 0.72 | NFE2L2 (0.39) | NFE2L2CYP3A4TSHR | |
| SCHEMBL3734671 | 0.72 | CYP1A1 (0.56) | PTGS1 | |
| SCHEMBL2096662 | 0.71 | CYP1A2 (0.52) | AHRTSHRCYP1A2PTGS1ALDH1A1 | |
| SCHEMBL16538337 | 0.70 | SCN9A (0.46) | ENPP1 | |
| SCHEMBL7969857 | 0.70 | NFE2L2 (0.49) | NFE2L2MEN1KMT2ACYP1A2 | |
| SCHEMBL3734674 | 0.69 | MAOB (0.53) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |