SCHEMBL7971487

SCHEMBL7971487

N#Cc1ccc([CH]c2cccc(Cl)n2)cc1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.35
NFE2L2 Q16236 5/20 0.35
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
FBP1 P09467 2/20 0.34
KDM4E B2RXH2 1/20 0.34
GAA P10253 1/20 0.34
L3MBTL1 Q9Y468 2/20 0.33
TSHR P16473 1/20 0.33
MAOA P21397 1/20 0.33
EGLN2 Q96KS0 1/20 0.33
MAPT P10636 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
TAS1R2 Q8TE23 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7969643 0.75 NFE2L2 (0.38) NFE2L2ALDH1A1GAATSHRMAPT
SCHEMBL7958651 0.73 NFE2L2 (0.56) NFE2L2ALDH1A1LMNAKDM4ETSHR
SCHEMBL7971708 0.73 AHR (0.41) NFE2L2ALDH1A1LMNATSHRMEN1
SCHEMBL7969202 0.73 NFE2L2 (0.38) NFE2L2LMNAGAAL3MBTL1TSHR
SCHEMBL7971462 0.72 NFE2L2 (0.39) NFE2L2KDM4EGAAL3MBTL1TSHR
SCHEMBL5253887 0.71 ALDH1A1 (0.50) MAOBALDH1A1LMNAFBP1KDM4E
SCHEMBL7968369 0.71 NFE2L2 (0.40) NFE2L2ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL7969857 0.70 NFE2L2 (0.49) MAOBNFE2L2FBP1MAPTMEN1
SCHEMBL7427498 0.68 NFE2L2 (0.45) NFE2L2ALDH1A1KDM4EL3MBTL1TSHR
SCHEMBL7427505 0.68 NFE2L2 (0.45) NFE2L2ALDH1A1KDM4EL3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed