Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 5/20 | 0.40 |
| ▸ | NOS3 | P29474 | 4/20 | 0.40 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | S100B | P04271 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3872243 | 0.82 | NOS1 (0.46) | NOS1NOS3NOS2RAD52SIGMAR1 | |
| SCHEMBL5260316 | 0.79 | NOS1 (0.34) | NOS1NOS3NOS2RAD52SLC6A4 | |
| SCHEMBL10425890 | 0.77 | RAD52 (0.40) | NOS1NOS3NOS2RAD52CYP1A2 | |
| SCHEMBL4884783 | 0.76 | SLC6A4 (0.40) | NOS1NOS3NOS2SIGMAR1SLC6A4 | |
| SCHEMBL1642010 | 0.76 | NOS1 (0.43) | NOS1NOS3NOS2RAD52SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3425848 | 0.74 | NOS1 (0.42) | NOS1NOS3NOS2RAD52SIGMAR1 | |
| SCHEMBL2574713 | 0.73 | CYP2D6 (0.46) | NOS1NOS3NOS2TLR8TLR7 | |
| SCHEMBL31357517 | 0.73 | CYP2D6 (0.46) | NOS1NOS3NOS2TLR8TLR7 | |
| SCHEMBL982159 | 0.71 | NOS2 (0.47) | NOS3NOS2RAD52S100BCD44 | |
| SCHEMBL28208071 | 0.70 | CD44 (0.39) | NOS3NOS2S100BCD44 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6204264-B1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| EP-0989123-A1 | Benzimidazole derivative, hair growth promoter and external composition for skin using the same | SHISEIDO COMPANY LIMITED (JP) | 2000-03-29 | — | — | EP | disclosed |