Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 4/20 | 0.38 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10425891 | 0.76 | TBK1 (0.39) | SLC6A4HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL9027471 | 0.76 | TYR (0.43) | HTR2A | |
| SCHEMBL14875929 | 0.76 | NOS1 (0.40) | SLC6A4NOS1NOS3NOS2MPO | |
| SCHEMBL7971745 | 0.76 | NOS1 (0.40) | SLC6A4NOS1NOS3NOS2SIGMAR1 | |
| SCHEMBL2170338 | 0.74 | SLC6A4 (0.49) | SLC6A4HTR2ASIGMAR1 | |
| SCHEMBL5260316 | 0.74 | NOS1 (0.34) | SLC6A4NOS1NOS3NOS2 | |
| SCHEMBL9444059 | 0.74 | SLC6A4 (0.49) | SLC6A4 | |
| SCHEMBL26618591 | 0.73 | TAAR1 (0.40) | HTR2AHTR2CHTR2BNOS1 | |
| SCHEMBL3872243 | 0.73 | NOS1 (0.46) | SLC6A4NOS1NOS3NOS2MPO | |
| SCHEMBL5158843 | 0.72 | NOS1 (0.43) | SLC6A4NOS1NOS3NOS2MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080045537-A1 | Chemical Compounds | SMITHKLINE BEECHAM CORPORATION | 2008-02-21 | — | — | US | disclosed |
| EP-1789045-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-05-30 | — | — | EP | disclosed |
| WO-2006023400-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080045537-A1 | Chemical Compounds | CCR5, CXCR4, CXCR3 | SLC6A4 3139/4885HTR2A 3235/4885HTR2C 2980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.