Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 15/20 | 0.45 |
| ▸ | BCL2 | P10415 | 5/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6847593 | 1.00 | MCL1 (0.45) | MCL1BCL2BCL2L1ALDH1A1HTT | |
| SCHEMBL6847596 | 1.00 | MCL1 (0.45) | MCL1BCL2BCL2L1ALDH1A1HTT | |
| SCHEMBL7971998 | 1.00 | MCL1 (0.45) | MCL1BCL2BCL2L1ALDH1A1HTT | |
| SCHEMBL27017367 | 0.90 | MCL1 (0.44) | MCL1BCL2BCL2L1GPR119UCHL1 | |
| SCHEMBL3264785 | 0.83 | UCHL1 (0.43) | MCL1GPR119UCHL1 | |
| SCHEMBL16370639 | 0.83 | MCL1 (0.43) | MCL1UCHL1 | |
| SCHEMBL16369937 | 0.83 | MCL1 (0.43) | MCL1UCHL1 | |
| SCHEMBL3264786 | 0.83 | UCHL1 (0.43) | MCL1GPR119UCHL1 | |
| SCHEMBL16369939 | 0.83 | MCL1 (0.43) | MCL1UCHL1 | |
| SCHEMBL23452261 | 0.81 | MCL1 (0.51) | MCL1UCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6288036-B1 | ANTIINFLAMMATORY, ANTIASTHMATIC, ANTIALLERGEN, AND ANALGESIC AGENTS; ARGININE-CONTAINING NONA- OR DECAPEPTIDES | SCIOS INC. | 2001-09-11 | — | — | US | disclosed |
| EP-0618809-B1 | BRADYKININ TYPE PEPTIDES | SCIOS NOVA INC (US) | 1998-08-19 | — | — | EP | disclosed |
| EP-0618809-A1 | BRADYKININ TYPE PEPTIDES | SCIOS NOVA INC. (US) | 1994-10-12 | — | — | EP | disclosed |
| EP-0618809-A4 | BRADYKININ TYPE PEPTIDES. | SCIOS NOVA INC (US) | 1994-07-28 | — | — | EP | disclosed |
| WO-1992018155-A1 | BRADYKININ TYPE PEPTIDES | NOVA TECHNOLOGY LIMITED PARTNERSHIP (US) | 1992-10-29 | — | — | WO | disclosed |