Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 6/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | TMEM97 | Q5BJF2 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7986498 | 0.99 | CCR3 (0.53) | CCR3SLC6A2SLC6A4SLC6A3TMEM97 | |
| SCHEMBL7985614 | 0.97 | CCR3 (0.58) | CCR3SLC6A2SLC6A4SLC6A3TMEM97 | |
| Hydrochloric Acid SCHEMBL7981966 | 0.97 | CCR3 (0.57) | CCR3SLC6A2SLC6A4SLC6A3TMEM97 | |
| SCHEMBL7983920 | 0.89 | CHRM4 (0.48) | CCR3SLC6A2SLC6A4TMEM97 | |
| Hydrochloric Acid SCHEMBL7981637 | 0.89 | CHRM4 (0.47) | CCR3SLC6A2SLC6A4TMEM97 | |
| SCHEMBL7989522 | 0.88 | CHRM4 (0.53) | CCR3 | |
| SCHEMBL7990681 | 0.88 | CHRM4 (0.43) | CCR3SLC6A2SLC6A4TMEM97 | |
| SCHEMBL7982970 | 0.88 | ADRA1D (0.45) | SLC6A2SLC6A4 | |
| SCHEMBL7985583 | 0.88 | ALDH1A1 (0.43) | — | |
| SCHEMBL7986609 | 0.88 | DRD3 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |