Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.46 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7982252 | 0.99 | ACKR3 (0.51) | ACKR3DRD2DRD3PRMT5WDR77 | |
| SCHEMBL7983390 | 0.97 | DRD2 (0.52) | ACKR3DRD2DRD3PRMT5WDR77 | |
| Hydrochloric Acid SCHEMBL7987158 | 0.96 | DRD2 (0.51) | ACKR3DRD2DRD3PRMT5WDR77 | |
| SCHEMBL7986609 | 0.83 | DRD3 (0.44) | DRD3CYP2D6ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL7986288 | 0.83 | DRD3 (0.51) | DRD2DRD3LMNAHTR2A | |
| SCHEMBL7985583 | 0.83 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2NPC1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL7982276 | 0.83 | GAA (0.44) | DRD2KDM4EALDH1A1SMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL7983890 | 0.82 | DRD3 (0.50) | DRD2DRD3LMNAHTR2A | |
| Hydrochloric Acid SCHEMBL7981722 | 0.82 | DRD3 (0.44) | DRD3CYP2D6ALDH1A1SMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL7983892 | 0.82 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2NPC1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6235731-B1 | REDUCING BLOOD LIPIDS, SUGARS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-22 | — | — | US | disclosed |