Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844426 | 0.83 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL1775436 | 0.77 | AGTR1 (0.38) | AGTR1AGTR2 | |
| SCHEMBL9291476 | 0.75 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL8866638 | 0.73 | DHODH (0.43) | — | |
| SCHEMBL7221466 | 0.72 | BRS3 (0.41) | — | |
| SCHEMBL8421730 | 0.70 | AGTR1 (0.37) | AGTR1 | |
| SCHEMBL3976472 | 0.70 | ABCB11 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7972086 | 0.70 | CMKLR1 (0.35) | — | |
| SCHEMBL8866651 | 0.70 | DHODH (0.44) | — | |
| SCHEMBL3264622 | 0.69 | AGTR1 (0.40) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232334-B1 | HAVE POTENT ANGIOTENSIN II ANTAGONISTIC ACTIVITY AND ANTIHYPERTENSIVE ACTIVITY, FOR TREATING CIRCULATORY SYSTEM DISEASES SUCH AS HYPERTENSIVE DISEASES, HEART DISEASES, STROKES, CEREBRAL APOPLEXY AND NEPHRITIS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-15 | — | — | US | claimed |