Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.49 |
| ▸ | FBP1 | P09467 | 2/20 | 0.48 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6798522 | 0.89 | NFE2L2 (0.60) | ALDH1A1TDP1NFE2L2FBP1VCP | |
| SCHEMBL6798527 | 0.89 | NFE2L2 (0.60) | ALDH1A1TDP1NFE2L2FBP1VCP | |
| SCHEMBL7501598 | 0.84 | NPC1 (0.46) | ALDH1A1TDP1FBP1CYP19A1MEN1 | |
| SCHEMBL14880346 | 0.81 | NFE2L2 (0.69) | ALDH1A1TDP1NFE2L2FBP1VCP | |
| SCHEMBL7971923 | 0.80 | CHRM5 (0.47) | NFE2L2FBP1MEN1KMT2AMAPT | |
| SCHEMBL5250012 | 0.76 | NFE2L2 (0.73) | ALDH1A1NFE2L2FBP1VCPCYP19A1 | |
| SCHEMBL8436212 | 0.74 | CYP11B2 (0.39) | CYP19A1MAPTPLAUMAOB | |
| SCHEMBL27887324 | 0.74 | NFE2L2 (0.65) | ALDH1A1TDP1NFE2L2FBP1VCP | |
| SCHEMBL6798937 | 0.74 | NFE2L2 (0.70) | ALDH1A1TDP1NFE2L2FBP1VCP | |
| SCHEMBL6798940 | 0.74 | NFE2L2 (0.70) | ALDH1A1TDP1NFE2L2FBP1VCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |