Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972129 | 0.84 | ALDH1A1 (0.50) | NPC1MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL14880514 | 0.79 | MAOB (0.58) | NPC1MAPTRAB9AAPPALDH1A1 | |
| SCHEMBL826834 | 0.77 | ALDH1A1 (0.50) | MAPTALDH1A1MAOBLMNAHTT | |
| SCHEMBL439935 | 0.77 | APP (0.64) | NPC1MAPTRAB9AAPPALDH1A1 | |
| SCHEMBL6798522 | 0.75 | NFE2L2 (0.60) | NPC1MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL6798527 | 0.75 | NFE2L2 (0.60) | NPC1MAPTRAB9AALDH1A1MEN1 | |
| Ethylene SCHEMBL27728657 | 0.74 | ALDH1A1 (0.47) | NPC1MAPTRAB9AALDH1A1MEN1 | |
| SCHEMBL28018804 | 0.74 | MAPT (0.79) | NPC1MAPTRAB9AAPPALDH1A1 | |
| SCHEMBL8436212 | 0.74 | CYP11B2 (0.39) | MAPTMAOBCYP19A1 | |
| SCHEMBL7968716 | 0.74 | POLB (0.41) | NPC1MAPTRAB9AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828739-B1 | BICYCLIC AMINES AS INSECTICIDES | SYNGENTA LTD (GB) | 2002-09-11 | — | — | EP | disclosed |