Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685269 | 0.71 | ALDH1A1 (0.47) | POLBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11685290 | 0.71 | HTT (0.56) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7958651 | 0.71 | NFE2L2 (0.56) | MAPTALDH1A1HPGDKDM4ERAB9A | |
| SCHEMBL7969202 | 0.71 | NFE2L2 (0.38) | POLBKMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL421678 | 0.70 | ALDH1A1 (0.69) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL7969643 | 0.70 | NFE2L2 (0.38) | MAPTALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7969303 | 0.69 | LRRK2 (0.49) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL11818057 | 0.69 | KMT2A (0.49) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7941715 | 0.69 | SMN1; SMN2 (0.64) | POLBMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL10944710 | 0.69 | SMN1; SMN2 (0.64) | POLBMAPTMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001017965-A2 | CYANOPIPERIDINES AS PESTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2001-03-15 | — | — | WO | disclosed |