SCHEMBL7969303

SCHEMBL7969303

CC(=O)Nc1ccc([CH]c2cncc(Cl)c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LRRK2 Q5S007 1/20 0.49
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
ALDH1A1 P00352 4/20 0.43
MAPT P10636 3/20 0.43
KDM4E B2RXH2 2/20 0.43
HPGD P15428 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
PIP4K2A P48426 1/20 0.43
TDP1 Q9NUW8 3/20 0.42
TP53 P04637 1/20 0.42
HSD17B10 Q99714 1/20 0.42
POLB P06746 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
HTT P42858 1/20 0.42
CA12 O43570 1/20 0.41
BRD4 O60885 1/20 0.41
NR1I2 O75469 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447661 0.76 RIPK1 (0.47) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL7968716 0.71 POLB (0.41) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL8436212 0.71 CYP11B2 (0.39) LRRK2MAPT
SCHEMBL7975159 0.71 AHR (0.53) ALDH1A1MAPTKDM4EHPGDTP53
SCHEMBL197282 0.70 SMN1; SMN2 (0.67) MEN1KMT2AALDH1A1MAPTTDP1
SCHEMBL7972136 0.69 POLB (0.46) MEN1KMT2AALDH1A1MAPTKDM4E
Hydrochloric Acid SCHEMBL9486219 0.69 SMN1; SMN2 (0.64) MEN1KMT2AALDH1A1MAPTTDP1
SCHEMBL7941715 0.69 SMN1; SMN2 (0.64) MEN1KMT2AALDH1A1MAPTKDM4E
SCHEMBL7941711 0.69 SMN1; SMN2 (0.64) MEN1KMT2AALDH1A1MAPTKDM4E
Methane SCHEMBL27454317 0.69 SMN1; SMN2 (0.64) MEN1KMT2AALDH1A1MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001017965-A2 CYANOPIPERIDINES AS PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2001-03-15 WO disclosed