SCHEMBL797214

SCHEMBL797214

C[SiH](C)[Zr](Cl)(Cl)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.33
HTR2A P28223 2/20 0.32
SIGMAR1 Q99720 4/20 0.31
BRD4 O60885 1/20 0.30
CCL2 P13500 1/20 0.30
KDM4E B2RXH2 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
CHRM2 P08172 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
NFKB1 P19838 1/20 0.30
CHRM3 P20309 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2C P28335 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898961 0.86 HTR6 (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL9578988 0.81 HTR2A (0.34) HTR6HTR2ASIGMAR1BRD4CCL2
Hydrochloric Acid SCHEMBL1065903 0.80 HTR2A (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
Hydrochloric Acid SCHEMBL9403731 0.80 HTR2A (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
Hydrochloric Acid SCHEMBL29370503 0.80 HTR2A (0.33) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL4445268 0.79 HTR2A (0.35) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL8409887 0.79 RET (0.36) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL137961 0.79 HTR2A (0.38) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL550007 0.79 HTR2A (0.38) HTR6HTR2ASIGMAR1BRD4CCL2
SCHEMBL3685967 0.79 HTR2A (0.38) HTR6HTR2ASIGMAR1BRD4CCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113717304-B Ethylene copolymer and preparation method and application thereof 中国石油化工股份有限公司 2023-07-21 CN disclosed
EP-1891122-B1 SUPPORTED POLYMERISATION CATALYSTS INEOS SALES UK LTD (GB) 2020-03-25 EP disclosed
US-10364309-B2 Supported polymerisation catalysts INEOS SALES (UK) LIMITED (GB) 2019-07-30 US disclosed
EP-2651981-B2 ACTIVATING SUPPORTS INEOS EUROPE AG (CH) 2019-01-23 EP disclosed
EP-2791189-B1 NOVEL POLYMERS INEOS EUROPE AG (CH) 2018-05-02 EP disclosed
EP-1539835-B1 SUPPORTED POLYMERISATION CATALYSTS INEOS SALES (UK) LTD (GB) 2017-10-25 EP disclosed
US-20170081446-A1 SUPPORTED POLYMERISATION CATALYSTS INNOVENE EUROPE LIMITED (GB) 2017-03-23 US disclosed
EP-2694290-B1 LAMINATE COMPRISING A POLYOLEFIN LAYER ADHERED TO A BASE LAYER INEOS EUROPE AG (CH) 2016-07-20 EP disclosed
EP-2651981-B1 ACTIVATING SUPPORTS INEOS EUROPE AG (CH) 2016-03-16 EP disclosed
US-9248630-B2 Laminate comprising a polyolefin layer adhered to a base layer INEOS EUROPE AG (CH) 2016-02-02 US disclosed
WO-2004055063-A1 SUPPORTED OLEFIN POLYMERIZATION CATALYST O & D TRADING LIMITED (GB) 2004-07-01 WO disclosed
WO-2004020487-A1 SUPPORTED POLYMERISATION CATALYSTS BP CHEMICALS LIMITED (GB) 2004-03-11 WO disclosed
WO-2004020488-A1 OLEFIN POLYMERISATION PROCESS BP CHEMICALS LIMITED (GB) 2004-03-11 WO disclosed
WO-2004018531-A1 SUPPORTED POLYMERISATION CATALYSTS BP CHEMICALS LIMITED (GB) 2004-03-04 WO disclosed
WO-2004018530-A1 SUPPORTED POLYMERISATION CATALYSTS BP CHEMICALS LIMITED (GB) 2004-03-04 WO disclosed
US-6586554-B1 Polyarylene and method for production thereof JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-07-01 US disclosed
US-20030116755-A1 Polyacene derivatives and production thereof JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-06-26 US disclosed
EP-1262469-A1 POLYACENE DERIVATIVES AND PRODUCTION THEREOF Japan Science and Technology Corporation (JP) 2002-12-04 EP disclosed
US-6417302-B1 REACTION PRODUCT OF DI(PENTAFLUOROPHENYL) BORINIC ACID AND ORGANOALUMINUM COMPOUND; OLEFIN POLYMERIZATION COORDINATION CATALYSTS BASELL POLYOLEFINE GMBH (DE) 2002-07-09 US disclosed
EP-1219657-A1 POLYARYLENE AND METHOD FOR PRODUCTION THEREOF Japan Science and Technology Corporation (JP) 2002-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030116755-A1 Polyacene derivatives and production thereof CBR1, HVCN1, H1-0 HTR6 1901/4885HTR2A 1503/4885SIGMAR1 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.