SCHEMBL7972471

SCHEMBL7972471

COc1cc(Cl)c2o[c]cc2c1

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.34
CYP1A1 P04798 1/20 0.32
CYP1B1 Q16678 1/20 0.32
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
ABL1 P00519 1/20 0.30
ABCB1 P08183 1/20 0.30
BCR P11274 1/20 0.30
PDE7A Q13946 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4125923 0.80 MAOB (0.40) ALDH1A1CYP1A1CYP1B1HSD17B1HSD17B2
SCHEMBL28502229 0.80 CA12 (0.36) ALDH1A1CYP1A1CYP1B1CYP1A2CYP2A6
SCHEMBL4455156 0.75 GPR35 (0.36) ALDH1A1
SCHEMBL16346014 0.72 NMT1 (0.31)
SCHEMBL767050 0.71 ERN1 (0.34) ALDH1A1
SCHEMBL19783319 0.69 CYP1A2 (0.41) ALDH1A1CYP1A1CYP1B1HSD17B1HSD17B2
SCHEMBL5546147 0.68 ALDH1A1 (0.32) ALDH1A1
SCHEMBL5539069 0.67 AHR (0.41)
SCHEMBL533282 0.67 CYP2A6 (0.47) ALDH1A1HSD17B1HSD17B2CYP1A2CYP2A6
SCHEMBL766977 0.66 HTR2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6268514-B1 TREATING INDUSTRIAL MATERIALS WITH NITROETHANE COMPOUND FOR PROTECTING AGAINST ATTACK AND DESTRUCTION BY MICROORGANISMS BASF AKTIENGESELLSCHAFT (DE) 2001-07-31 US disclosed