Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972503 | 0.86 | KMT2A (0.60) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL17063917 | 0.80 | NPC1 (0.64) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL10073073 | 0.79 | KMT2A (0.80) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL11418358 | 0.76 | HTT (0.58) | HPGDTSHRNPC1HCRTR1HTT | |
| SCHEMBL4724490 | 0.73 | L3MBTL1 (0.58) | LMNAHPGDSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL6360387 | 0.73 | GAA (0.57) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL10073070 | 0.72 | LMNA (0.80) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL123523 | 0.72 | L3MBTL1 (0.64) | KMT2AMEN1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL12113209 | 0.72 | NPC1 (0.61) | LMNAHPGDSMN1; SMN2L3MBTL1TSHR | |
| SCHEMBL558028 | 0.72 | KMT2A (0.66) | KMT2AMEN1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |