Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972508 | 0.86 | KMT2A (0.61) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL17063917 | 0.79 | NPC1 (0.64) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL10073073 | 0.78 | KMT2A (0.80) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL4724490 | 0.75 | L3MBTL1 (0.58) | HPGDLMNASMN1; SMN2TSHRNPC1 | |
| SCHEMBL10073070 | 0.74 | LMNA (0.80) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL5812840 | 0.72 | CNR2 (0.59) | HPGDL3MBTL1ALDH1A1GAA | |
| SCHEMBL6360387 | 0.72 | GAA (0.57) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL5717635 | 0.71 | ALDH1A1 (0.73) | KMT2AALDH1A1GAAHTT | |
| SCHEMBL123523 | 0.71 | L3MBTL1 (0.64) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL12113209 | 0.71 | NPC1 (0.61) | HPGDLMNASMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | claimed |
| WO-2001055109-A1 | AROMATIC AMIDES ACTING ON MELANOCORTIN RECEPTORS | MELACURE THERAPEUTICS AB (SE) | 2001-08-02 | — | — | WO | disclosed |