Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972579 | 0.72 | CYP2D6 (0.40) | CYP2D6 | |
| SCHEMBL18938519 | 0.68 | NPC1 (0.77) | MAPTALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL8015244 | 0.67 | HSD11B1 (0.40) | ALDH1A1SMN1; SMN2CYP2D6NPC1RAB9A | |
| SCHEMBL27406964 | 0.64 | NOTUM (0.71) | NOTUM | |
| SCHEMBL28257682 | 0.64 | NOTUM (0.60) | MAPTALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL7975329 | 0.63 | CYP2D6 (0.48) | ALDH1A1HPGDMEN1KMT2ACYP2D6 | |
| SCHEMBL7975326 | 0.63 | CYP2D6 (0.48) | ALDH1A1HPGDMEN1KMT2ACYP2D6 | |
| SCHEMBL28175932 | 0.62 | NOTUM (0.57) | MAPTALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL28257681 | 0.62 | NOTUM (0.58) | MAPTALDH1A1TSHRSMN1; SMN2HPGD | |
| SCHEMBL8419841 | 0.62 | CYP2D6 (0.47) | MAPTALDH1A1TSHRHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |