Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.53 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.53 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | TLR4 | O00206 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316426 | 0.86 | NPC1 (0.50) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL31538753 | 0.86 | NPC1 (0.50) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL9315739 | 0.84 | MEN1 (0.54) | NPC1RAB9ANFE2L2TFEBBCHE | |
| SCHEMBL11410414 | 0.81 | NFE2L2 (0.49) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL793033 | 0.75 | PRMT1 (0.73) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL793032 | 0.75 | PRMT1 (0.73) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL27394119 | 0.75 | PRMT1 (0.73) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL4019329 | 0.74 | NFE2L2 (0.79) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL1603719 | 0.74 | NFE2L2 (0.79) | NPC1RAB9ANFE2L2TRPA1TFEB | |
| SCHEMBL7915752 | 0.74 | NFE2L2 (0.79) | NPC1RAB9ANFE2L2TRPA1TFEB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-5043539-A | — | — | None | — | — | JP | disclosed |
| US-6277545-B1 | FORMING PHOTORESIST, IRADIATING WITH LASER | PIONEER ELECTRONIC CORPORATION (JP) | 2001-08-21 | — | — | US | disclosed |
| JP-H0543539-A | ALPHA-(O-(METHOXY)STYRYL)-N-PHENYLNITRONE AND CONTRAST ENHANCED MATERIAL | SHIN ETSU CHEM CO LTD | 1993-02-23 | — | — | JP | disclosed |