Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | TFEB | P19484 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9316426 | 0.88 | NPC1 (0.50) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL31538753 | 0.88 | NPC1 (0.50) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL7972705 | 0.84 | NPC1 (0.57) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL31538748 | 0.82 | NFE2L2 (0.50) | RAB9ANPC1MAPTLMNABCHE | |
| SCHEMBL9315446 | 0.82 | NFE2L2 (0.50) | RAB9ANPC1MAPTLMNABCHE | |
| SCHEMBL31538757 | 0.81 | TSHR (0.49) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9315666 | 0.81 | TSHR (0.49) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL31538752 | 0.75 | MAPT (0.49) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL9315516 | 0.75 | MAPT (0.49) | MEN1KMT2ARAB9ANPC1MAPT | |
| SCHEMBL27635723 | 0.73 | TP53 (0.66) | MEN1KMT2ARAB9AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5310620-A | Alkali-soluble nitrone compounds and contrast enhanced material comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1994-05-10 | — | — | US | disclosed |