Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 1/20 | 0.37 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8419841 | 0.79 | CYP2D6 (0.47) | HSD11B1CYP2D6 | |
| Water SCHEMBL7778613 | 0.78 | CYP2D6 (0.46) | HSD11B1CYP2D6 | |
| SCHEMBL7972579 | 0.74 | CYP2D6 (0.40) | CYP2D6 | |
| SCHEMBL7972856 | 0.73 | CYP2D6 (0.39) | HSD11B1CYP2D6 | |
| Trifluoroacetic Acid SCHEMBL21819343 | 0.71 | EPHX2 (0.45) | GAATRPV1OPRM1OPRD1OPRK1 | |
| SCHEMBL7972857 | 0.70 | HSD11B1 (0.62) | HSD11B1MGLLGAALIPECYP2D6 | |
| SCHEMBL8015244 | 0.69 | HSD11B1 (0.40) | HSD11B1CYP2D6 | |
| SCHEMBL2517888 | 0.68 | EPHX1 (0.58) | HTR2CLIPETRPV1OPRM1OPRD1 | |
| SCHEMBL23657648 | 0.66 | TRPV1 (0.78) | TRPV1 | |
| SCHEMBL12576441 | 0.66 | HSD11B1 (1.00) | HSD11B1MGLLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6291464-B1 | POTENTIATION OF THE CHOLINERGIC ACTIVITY; THERAPEUTIC TREATMENT OF AMNESIA, DEMENTIA OR SENILE DEMENTIA | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-09-18 | — | — | US | disclosed |