Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.57 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.49 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.41 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.38 |
| ▸ | RXRB | P28702 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7979062 | 0.93 | ABCB1 (0.54) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL7974209 | 0.81 | ABCB1 (0.46) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL7974197 | 0.80 | MRGPRX4 (0.51) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL5270656 | 0.79 | MRGPRX4 (0.56) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL1839684 | 0.78 | MRGPRX4 (0.63) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL7962737 | 0.77 | ABCB1 (0.39) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL13481244 | 0.76 | MRGPRX4 (0.54) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL27605775 | 0.76 | ADRB1 (0.67) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL11196314 | 0.76 | ADRB2 (0.73) | ADRB2ADRB1ADRB3HTR1ATSHR | |
| SCHEMBL13148924 | 0.76 | ADRB1 (0.77) | ADRB2ADRB1ADRB3HTR1ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |