Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.51 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 3/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7972678 | 0.92 | ALDH1A1 (0.45) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL7972959 | 0.82 | MRGPRX4 (0.49) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL7972957 | 0.80 | ADRB2 (0.57) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL7962763 | 0.78 | LMNA (0.42) | PPARASMN1; SMN2PPARGLTB4RALDH1A1 | |
| SCHEMBL15283161 | 0.78 | TSHR (0.50) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL7974235 | 0.78 | SMN1; SMN2 (0.43) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL7972637 | 0.78 | LTB4R (0.43) | PPARASMN1; SMN2PPARGLTB4RLTB4R2 | |
| SCHEMBL5353949 | 0.76 | ADRB2 (0.47) | MRGPRX4ADRB2ADRB1ADRB3HTR1A | |
| SCHEMBL7976476 | 0.76 | PPARA (0.42) | TSHRPPARASMN1; SMN2PPARGABCB1 | |
| SCHEMBL5270656 | 0.75 | MRGPRX4 (0.56) | MRGPRX4ADRB2ADRB1ADRB3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6248766-B1 | CARDIOVASCULAR DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-06-19 | — | — | US | disclosed |