Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3458396 | 0.78 | NAAA (0.52) | ALDH1A1MEN1KMT2AHTTPOLB | |
| SCHEMBL3459713 | 0.74 | ALDH1A1 (0.49) | HPGDALDH1A1HSD17B10KMT2AMAPT | |
| SCHEMBL1525473 | 0.74 | HPGD (0.53) | HPGDL3MBTL1ALDH1A1KMT2ACYP1A2 | |
| SCHEMBL3459574 | 0.72 | HPGD (0.60) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL4050708 | 0.71 | HPGD (0.46) | HPGDL3MBTL1ALDH1A1MEN1KMT2A | |
| SCHEMBL3458943 | 0.71 | RECQL (0.46) | HPGDKDM4EALDH1A1HSD17B10MEN1 | |
| SCHEMBL20076975 | 0.69 | ELANE (0.60) | HPGDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1927948 | 0.69 | HPGD (0.56) | HPGDL3MBTL1ALDH1A1HSD17B10KMT2A | |
| SCHEMBL28020408 | 0.68 | HPGD (0.59) | HPGDKDM4EL3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL10294125 | 0.68 | MLYCD (0.57) | HPGDALDH1A1MEN1KMT2AHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001007409-A1 | CARBAZOLE DERIVATIVES AND THEIR USE AS NEUROPEPTIDE Y5 RECEPTOR LIGANDS | ASTRAZENECA UK LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |