Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 6/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR6 | P46095 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.37 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10172719 | 0.97 | HDAC1 (0.43) | HDAC1KDM4EALDH1A1HSD17B10AKR1C3 | |
| SCHEMBL10140161 | 0.83 | ACHE (0.40) | — | |
| SCHEMBL10140278 | 0.75 | SMN1; SMN2 (0.48) | AKR1C3POLBMEN1HTTKMT2A | |
| SCHEMBL10140272 | 0.74 | MEN1 (0.48) | AKR1C3MAPTMEN1HTTKMT2A | |
| SCHEMBL7961501 | 0.74 | ACHE (0.35) | GPR6 | |
| SCHEMBL16258930 | 0.74 | RAB9A (0.52) | KDM4EAKR1C3MAPTMEN1KMT2A | |
| SCHEMBL16258988 | 0.73 | HDAC1 (0.47) | HDAC1HDAC2 | |
| SCHEMBL16258974 | 0.73 | RAB9A (0.43) | KDM4EALDH1A1HPGDAKR1C3MAPT | |
| SCHEMBL10172717 | 0.67 | NPSR1 (0.39) | HSD17B10MAPTGPR6MEN1KMT2A | |
| SCHEMBL16258931 | 0.67 | LRRK2 (0.42) | HDAC1KDM4EALDH1A1HDAC2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143039-A2 | HETEROCYCLIC COMPOUNDS AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2009-11-26 | — | — | WO | disclosed |