Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.54 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.54 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7984991 | 0.90 | KAT6A (0.54) | KAT6AKMT2ASMPD1PLA2G4BTHRB | |
| SCHEMBL7985855 | 0.87 | KAT6A (0.52) | KAT6AKMT2ANR1H4MAPK1MEN1 | |
| SCHEMBL7985774 | 0.84 | TSHR (0.55) | KMT2APLA2G4BMEN1 | |
| SCHEMBL16409554 | 0.83 | PLA2G4B (0.60) | KAT6AKMT2ASMPD1PLA2G4BTHRB | |
| SCHEMBL7973298 | 0.80 | SMPD1 (0.67) | KAT6AKMT2ASMPD1PLA2G4BTHRB | |
| SCHEMBL1436145 | 0.79 | THRB (0.65) | KMT2ASMPD1PLA2G4BTHRBNR1H4 | |
| SCHEMBL3315904 | 0.79 | KMT2A (0.84) | KMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL27903063 | 0.79 | KMT2A (0.64) | KAT6AKMT2ASMPD1PLA2G4BTHRB | |
| SCHEMBL11056943 | 0.78 | KMT2A (0.62) | KAT6AKMT2ASMPD1PLA2G4BTHRB | |
| SCHEMBL7765680 | 0.78 | THRB (0.63) | KAT6AKMT2ASMPD1PLA2G4BTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |