Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.61 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.56 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769343 | 0.92 | KMT2A (0.73) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL27903063 | 0.85 | KMT2A (0.64) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL3315904 | 0.85 | KMT2A (0.84) | KMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL1436145 | 0.85 | THRB (0.65) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL5250834 | 0.85 | HPGD (0.56) | KMT2ANR1H4KAT6AMAPK1MEN1 | |
| SCHEMBL5202638 | 0.84 | KMT2A (0.62) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL11056943 | 0.84 | KMT2A (0.62) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL201450 | 0.84 | KMT2A (0.62) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL15474092 | 0.84 | THRB (0.63) | THRBKMT2ASMPD1PLA2G4BNR1H4 | |
| SCHEMBL8414531 | 0.83 | KMT2A (0.65) | THRBKMT2ASMPD1PLA2G4BNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6331628-B1 | REACTING A SUBSTITUTED HALOBENZENE WITH POTASSIUM, SODIUM AND/OR ZINC CYANIDE IN THE PRESENCE OF A METALLIC CATALYST | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2001-12-18 | — | — | US | disclosed |
| EP-0765879-B1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO CO (JP) | 2001-02-14 | — | — | EP | disclosed |
| US-5861429-A | MITICIDES AND ANTHELMINTICS | SANKYO COMPANY, LIMITED (JP) | 1999-01-19 | — | — | US | disclosed |
| US-5672722-A | COUMARAN OR CHROMAN DERIVATIVES INCLUDED IN SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL PREVENT FADING AND DISCOLORATION OF IMAGES | FUJI PHOTO FILM CO., LTD. (JP) | 1997-09-30 | — | — | US | disclosed |
| EP-0765879-A1 | 13-Substituted milbemycin 5-oxime derivatives, their preparation and their use against insects and other pests | SANKYO COMPANY LIMITED (JP) | 1997-04-02 | — | — | EP | disclosed |
| US-5567578-A | HIGH FASTNESS TO LIGHT ALL FROM THE HIGH-DENSITY AREAS TO THE LOW-DENSITY AREAS | FUJI PHOTO FILM CO., LTD. (JP) | 1996-10-22 | — | — | US | disclosed |
| US-5543275-A | PYRAZOLO(1,5-B)(1,2,4)TRIAZOLE MAGENTA COUPLER | FUJI PHOTO FILM CO., LTD. (JP) | 1996-08-06 | — | — | US | disclosed |
| US-5534390-A | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1996-07-09 | — | — | US | disclosed |