Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | RXRA | P19793 | 17/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974626 | 0.85 | HCAR3 (0.46) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7673319 | 0.84 | RXRA (0.56) | HCAR3RXRAPPARG | |
| SCHEMBL7979349 | 0.84 | HCAR3 (0.44) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7672615 | 0.82 | HCAR3 (0.51) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7810643 | 0.82 | RXRA (0.53) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7810595 | 0.81 | HCAR3 (0.45) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7974544 | 0.81 | HCAR3 (0.45) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7976850 | 0.81 | RXRA (0.54) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7963014 | 0.81 | HCAR3 (0.45) | HCAR3RXRAPPARGGBA1 | |
| SCHEMBL7963017 | 0.81 | HCAR3 (0.45) | HCAR3RXRAPPARGGBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313148-B1 | FOR THERAPY OF PAIN PAIN ASSOCIATED WITH JOINT CONDITIONS SUCH AS RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS, POSTOPERATIVE PAIN, POST-PARTUM PAIN, THE PAIN ASSOCIATED WITH DENTAL CONDITIONS SUCH AS DENTAL CARIES AND GINGIVITIS | ZENECA LIMITED (GB) | 2001-11-06 | — | — | US | claimed |