SCHEMBL7973483

SCHEMBL7973483

Cc1ccc(S(=O)(=O)OCCCCC(OS(=O)(=O)c2ccc(C)cc2)C(=O)OC(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PSMD10 O75832 1/20 0.37
CYP3A4 P08684 1/20 0.36
STAT3 P40763 1/20 0.36
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
MDM2 Q00987 1/20 0.34
ALDH1A1 P00352 6/20 0.34
LMNA P02545 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA9 Q16790 2/20 0.34
KDM4E B2RXH2 2/20 0.34
CA2 P00918 1/20 0.34
PLA2G2C Q5R387 1/20 0.34
HPGD P15428 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
CYP24A1 Q07973 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7973217 0.96 PSMD10 (0.38) PSMD10CYP3A4STAT3KMT2ANPC1
SCHEMBL7064465 0.91 STAT3 (0.38) PSMD10CYP3A4STAT3KMT2ANPC1
SCHEMBL7959970 0.89 RAB9A (0.36) KMT2ARAB9AALDH1A1HPGD
SCHEMBL7976224 0.88 KMT2A (0.42) PSMD10STAT3KMT2AALDH1A1LMNA
SCHEMBL7975853 0.88 PSMD10 (0.43) PSMD10STAT3KMT2ARAB9AALDH1A1
SCHEMBL7971396 0.85 RAB9A (0.37) KMT2ARAB9AALDH1A1HPGD
SCHEMBL7973218 0.85 PLA2G2C (0.40) PSMD10STAT3KMT2AALDH1A1LMNA
SCHEMBL7959885 0.84 PSMD10 (0.43) PSMD10STAT3KMT2ARAB9AALDH1A1
SCHEMBL7959891 0.84 KMT2A (0.46) PSMD10STAT3KMT2AALDH1A1LMNA
SCHEMBL7972874 0.84 PLA2G2C (0.43) PSMD10STAT3ALDH1A1LMNAPLA2G2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172234-B1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-09 US disclosed
EP-0976729-A1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed