SCHEMBL7975853

SCHEMBL7975853

COC(=O)C(CCCCOS(=O)(=O)c1ccc(C)cc1)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PSMD10 O75832 1/20 0.43
STAT3 P40763 2/20 0.40
PLA2G2C Q5R387 1/20 0.37
MAPT P10636 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
SIRT5 Q9NXA8 1/20 0.36
KMT2A Q03164 3/20 0.36
MEN1 O00255 1/20 0.36
GAA P10253 2/20 0.36
ALDH1A1 P00352 4/20 0.35
PLCG1 P19174 1/20 0.35
RAB9A P51151 1/20 0.35
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA9 Q16790 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959885 0.96 PSMD10 (0.43) PSMD10STAT3PLA2G2CMAPTCTDSP1
SCHEMBL7066596 0.91 STAT3 (0.42) PSMD10STAT3MAPTCTDSP1SIRT5
SCHEMBL7976224 0.90 KMT2A (0.42) PSMD10STAT3PLA2G2CMAPTKMT2A
SCHEMBL7972944 0.89 KMT2A (0.39) KMT2AMEN1RAB9ACA12CA9
SCHEMBL7973483 0.88 PSMD10 (0.37) PSMD10STAT3PLA2G2CKMT2AALDH1A1
SCHEMBL7973218 0.87 PLA2G2C (0.40) PSMD10STAT3PLA2G2CKMT2AMEN1
SCHEMBL7959891 0.86 KMT2A (0.46) PSMD10STAT3MAPTKMT2AMEN1
SCHEMBL7972874 0.86 PLA2G2C (0.43) PSMD10STAT3PLA2G2CALDH1A1
SCHEMBL7976100 0.85 CYP24A1 (0.37) PSMD10STAT3KMT2AGAAALDH1A1
SCHEMBL7972978 0.85 KMT2A (0.40) KMT2AMEN1RAB9ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172234-B1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-09 US disclosed
EP-0976729-A1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed