SCHEMBL7976224

SCHEMBL7976224

CCOC(=O)C(CCCCOS(=O)(=O)c1ccc(C)cc1)OS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MEN1 O00255 1/20 0.42
PSMD10 O75832 1/20 0.39
GAA P10253 1/20 0.39
ALDH1A1 P00352 7/20 0.38
LMNA P02545 3/20 0.38
STAT3 P40763 1/20 0.38
MAPT P10636 3/20 0.37
POLB P06746 1/20 0.37
PLA2G2C Q5R387 1/20 0.37
CRHBP P24387 1/20 0.37
CRHR2 Q13324 1/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
KDM4E B2RXH2 2/20 0.37
MAPK1 P28482 1/20 0.37
HPGD P15428 1/20 0.37
RECQL P46063 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HSD17B10 Q99714 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7959891 0.96 KMT2A (0.46) KMT2AMEN1PSMD10GAAALDH1A1
SCHEMBL7973218 0.92 PLA2G2C (0.40) KMT2AMEN1PSMD10GAAALDH1A1
SCHEMBL7064469 0.91 KMT2A (0.42) KMT2AMEN1PSMD10GAAALDH1A1
SCHEMBL7972874 0.91 PLA2G2C (0.43) PSMD10ALDH1A1LMNASTAT3PLA2G2C
SCHEMBL7969622 0.90 TDP1 (0.42) KMT2AMEN1ALDH1A1MAPTPOLB
SCHEMBL7975853 0.90 PSMD10 (0.43) KMT2AMEN1PSMD10GAAALDH1A1
SCHEMBL7960303 0.88 PLA2G2C (0.43) KMT2AMEN1PSMD10ALDH1A1LMNA
SCHEMBL7971365 0.88 KMT2A (0.40) KMT2AMEN1PSMD10GAAALDH1A1
SCHEMBL7973483 0.88 PSMD10 (0.37) KMT2APSMD10ALDH1A1LMNASTAT3
SCHEMBL7969820 0.86 LMNA (0.46) LMNAMAPTHPGDCA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6172234-B1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-01-09 US disclosed
EP-0976729-A1 Optically active cyclic amino acid ester derivatives and processes for producing the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-02-02 EP disclosed