Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
| ▸ | CCR6 | P51684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7991264 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7004051 | 0.85 | HSD17B10 (0.49) | MEN1KMT2AMAPTALDH1A1MAPK1 | |
| SCHEMBL7001550 | 0.79 | MAOB (0.49) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL11263544 | 0.77 | MAPK1 (0.56) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL28301064 | 0.76 | LMNA (0.47) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL29435299 | 0.73 | MAPT (0.67) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL512092 | 0.73 | MAPT (0.67) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL6998064 | 0.73 | MEN1 (0.55) | MEN1KMT2AMAPTALDH1A1HTT | |
| SCHEMBL15641270 | 0.70 | AKR1C3 (0.63) | ALDH1A1LMNACYP1A2CYP2C19TAS1R3 | |
| SCHEMBL15641272 | 0.70 | AKR1C3 (0.63) | ALDH1A1LMNACYP1A2CYP2C19TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200970-B1 | FOR TREATING A DISEASE ASSOCIATED WITH OVERSTIMULATION OF AN AMPA RECEPTOR, OR HYPERACTIVITY OF AN EXCITATORY AMINO ACID | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | disclosed |