Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7973493 | 0.86 | MEN1 (0.47) | MEN1KMT2AMAPTALDH1A1TTR | |
| SCHEMBL28444749 | 0.79 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL6998064 | 0.79 | MEN1 (0.55) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL7004051 | 0.75 | HSD17B10 (0.49) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| SCHEMBL145997 | 0.73 | TDP1 (0.64) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL31144295 | 0.73 | TDP1 (0.64) | MEN1KMT2AMAPTPOLBALDH1A1 | |
| SCHEMBL7001550 | 0.73 | MAOB (0.49) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL8389103 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2AMAPTALDH1A1HPGD | |
| SCHEMBL1679243 | 0.70 | AKR1C3 (0.55) | ALDH1A1HPGDCYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16550142 | 0.70 | L3MBTL1 (0.71) | MAPTALDH1A1CYP1A2CYP2C19TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200970-B1 | FOR TREATING A DISEASE ASSOCIATED WITH OVERSTIMULATION OF AN AMPA RECEPTOR, OR HYPERACTIVITY OF AN EXCITATORY AMINO ACID | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-03-13 | — | — | US | disclosed |