Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 7/20 | 0.46 |
| ▸ | RAB9A | P51151 | 7/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | GRK6 | P43250 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6782970 | 0.81 | MAOA (0.56) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL5733868 | 0.78 | NPC1 (0.45) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL5737775 | 0.77 | ACLY (0.44) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL23176649 | 0.76 | KDM4E (0.53) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7993840 | 0.76 | GRK6 (0.50) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL5734523 | 0.75 | ACLY (0.44) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL7997880 | 0.75 | ESR1 (0.50) | MAPTNPC1RAB9AKDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL6915336 | 0.74 | GAA (0.41) | MAPTNPC1RAB9AKDM4EHSD17B10 | |
| SCHEMBL7973727 | 0.73 | GRK6 (0.55) | MAPTNPC1RAB9AKDM4EMEN1 | |
| SCHEMBL6782984 | 0.73 | GAA (0.60) | KDM4EMEN1KMT2AALDH1A1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001055143-A1 | BENZOXAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |
| WO-2001055136-A1 | BENZOXAZOLE DERIVATIVES AND THEIR USE AS PESTICIDES | SYNGENTA LIMITED (GB) | 2001-08-02 | — | — | WO | disclosed |